Let’s Talk… My Experience with GLP-1 Medications for Weight Loss!!

Back story. For those of y’all who don’t know me or have never met me, I’m on a weight loss journey that started last October. I went on a compounded semaglutide. I lost 16 lbs but had some bad side effects that I fought through. I stopped when we went to France for Christmas and New Years with the understanding (with my PCP) that I would switch to Zepbound when I returned. 

Current story. Zepbound is Mounjaro but marketed for weight loss. It’s extremely popular in that there are 25k prescriptions being written for it each week. I had some issues getting the medication and started January 22. My insurance company refused to cover it, but I used the Zepbound savings card that the manufacturer makes available on its website. I had what I would call significant weight loss the first two weeks with very mild side effects. Since then I’ve had stable results but noticed that it is really affecting my appetite in that I’m eating much less. I’ve noticed that I snack virtually none of the time. Keep in mind I was on the lowest dose (2.5 mg) for the first four weeks. I stepped up to 5mg a week ago and don’t anticipate stepping up again. 

Other things:

• I noticed that Zepbound dramatically changed my appetite for alcohol. It’s weird in that I’m almost repulsed by beer and hard alcohol. This is consistent with study participants in that it was noticeable. 
• If you like to eat, it’s going to slow you down quite significantly. It slows your digestion so you are just not going to want to eat or be able to eat as much 
• Lastly, be aware of foods you need to avoid or foods that disagree with you while on medication.  I can’t handle greasy foods, dairy or starches. Again I read the website and this is consistent with what they tell you to avoid but I guess I need to learn by putting my hand on the fire. 

Final takeaway. If you have tried other GLP1 medications without much success, talk to your doctor and see if there’s another medication out there that can help you. It’s a personal decision and you have to find the right medication that works with your body.

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